Fundamentals of Early Clinical Drug Development : From Synthesis Design to Formulation by
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Publication details: Hoboken, N.J. : Wiley-Interscience, ©2006
Dissertation note: Reflections on process research II / Edward J.J. Grabowski --
Development and scale-up of a heterocyclic cross-coupling for the synthesis of 5-(2-(3-methyl-3H-imidazol-4-yl)thieno(3,2-b)pyridin-7-yl)amino-2-methyl-1H-indol / John A. Ragan --
Large-scale enantioselective preparation of 2E,7E, 5S,6R, 5-hydroxy-6-methyl-8-phenyl-octa-2,7-dienoic acid, a key fragment for the formal total synthesis of the anti-tumor agent cryptophycin 52 / James Aikins ... [et al.] --
Efforts toward a commercially viable route and process to the synthesis of HIV PI GW640385X / John C. Roberts ... [et al.] --
Development of an asymmetric synthesis of ABT-100 / Albert W. Kruger ... [et al.] --
Asymmetric hydrogenation: a new route to pregabalin / Rex Jennings ... [et al.] --
Responsibilities of the process chemist: beyond synthetic organic chemistry / Stéphane Caron --
Outsourcing: the challenge of science, speed, and quality / Simone Andler-Burzlaff, Jason Bertola, and Roger E. Marti --
Automation and the changing face of process research in the pharmaceutical industry / Edward J. Delaney ... [et al.] --
Large scale synthesis: an engineering perspective / Joseph H. Childers, Jr. --
Synthesis and application of radioisotopes in pharmaceutical research and development / Larry E. Weaner and David C. Hoerr --
Selection of the drug form in exploratory development / George J. Quallich --
Strategies to control particle size of active pharmaceutical ingredients / David J. am Ende and Peter R. Rose --
Challenges in early formulation: turning drug substance into drug product / Mark H. Kleinman and Beeah Lee --
Intellectual property and early development / Maria I. Shchuka.
Availability: Items available for loan: RAJUVAS Library (1)Call number: LZ3 SYN 2006.
